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dc.contributor.authorSoriano-Maldonado, Alberto-
dc.contributor.authorHidalgo, María-
dc.contributor.authorArteaga, Patricia-
dc.contributor.authorPascual-Teresa, Sonia de-
dc.contributor.authorNova, Esther-
dc.date.accessioned2015-11-05T09:49:17Z-
dc.date.available2015-11-05T09:49:17Z-
dc.date.issued2014-12-
dc.identifierissn: 1436-6215-
dc.identifier.citationEuropean Journal of Nutrition 53(8): 1645-1657 (2014)-
dc.identifier.urihttp://hdl.handle.net/10261/124505-
dc.description.abstract[Purpose] The aim of the present study was to investigate the effects of the consumption of two cloudy apple juices with different polyphenol and vitamin C contents on antioxidant status, cardiometabolic and inflammation markers in healthy young adults.-
dc.description.abstract[Methods] Twenty subjects, aged 21-29 years, completed a randomized crossover study. At each 4-week intervention period, the volunteers randomly consumed two glasses (2 × 250 mL/day) of either a vitamin C-rich apple juice (VCR) (60 mg/L vitamin C and 510 mg catechin equivalent/L) or a polyphenol-rich (PR) juice (22 mg/L vitamin C and 993 mg catechin equivalent/L). Blood and urine samples were collected throughout the study, and markers of antioxidant status, glucose metabolism, lipid profile and inflammation were measured.-
dc.description.abstract[Results] The comparison of the post-intervention minus pre-intervention change revealed differential results in HOMA index, total cholesterol, ICAM-1 and VCAM-1 (P < 0.05) across juices. During the VCR period, plasma antioxidant activity (FRAP) increased (P = 0.031), while ICAM-1 and total cholesterol showed a trend to decrease (P = 0.060 and P = 0.094, respectively). During the PR period, plasma insulin and HOMA increased, and total glutathione decreased (P < 0.05).-
dc.description.abstract[Conclusions] A joint consumption of apple juice natural antioxidants such as vitamin C and polyphenols might provide mild favorable effects on cardiometabolic markers, as compared to apple polyphenols alone.-
dc.description.sponsorshipThe authors acknowledge funding from the Spanish Ministry of Science and Innovation (MICINN) (AGL2009-10415 and AGL2012-30803). ASM and MH were supported by CSIC (JAE-intro and JAE-pre, respectively).-
dc.publisherSpringer-
dc.relation.isversionofPostprint-
dc.rightsopenAccess-
dc.titleEffects of regular consumption of vitamin C-rich or polyphenol-rich apple juice on cardiometabolic markers in healthy adults: a randomized crossover trial-
dc.typeartículo-
dc.identifier.doi10.1007/s00394-014-0670-7-
dc.relation.publisherversionhttp://doi.org/10.1007/s00394-014-0670-7-
dc.date.updated2015-11-05T09:49:18Z-
dc.description.versionPeer Reviewed-
dc.language.rfc3066eng-
dc.contributor.funderMinisterio de Ciencia e Innovación (España)-
dc.contributor.funderEuropean Commission-
dc.contributor.funderConsejo Superior de Investigaciones Científicas (España)-
dc.relation.csic-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004837es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003339es_ES
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