English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/124440
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Simultaneous release of peptides and phenolics with antioxidant, ACE-inhibitory and anti-inflammatory activities from pinto bean (Phaseolus vulgaris L. var. pinto) proteins by subtilisins

AutorGarcía Mora, Patricia ; Frías, Juana ; Peñas, Elena ; Zielinski, Henryk; Giménez-Bastida, J. A. ; Wiczkowski, W.; Zielinska, C.; Martínez Villaluenga, Cristina
Fecha de publicaciónoct-2015
EditorElsevier
CitaciónJournal of Functional Analysis 18(Part A): 319-332 (2015)
ResumenProduction of novel functional ingredients from legume proteins is a valuable strategy to boost their food use and intake. Aimed at a better exploitation of the functional properties of pinto bean hydrolysates, the effectiveness of two subtilisins (Alcalase and Savinase) for the simultaneous release of bioactive peptides and phenolics with antioxidant, angiotensin I converting enzyme (ACE) inhibitory and anti-inflammatory activities was investigated. A higher proteolytic efficiency was observed for Alcalase that increased the concentration of small peptides in hydrolysates after 120 min. Savinase improved hydroxycinnamic acids and flavonoid contents in hydrolysates after 90 min due to its higher esterase activity. The most active hydrolysates combined potent free radical scavenging (326¿348 mmol TE/g), ACE inhibitory (IC50 = 0.22¿0.26 mg/mL) and anti-inflammatory (28¿16% inhibition) activities. Peptide characterization of active hydrolysates confirmed the presence of bioactive fragments derived from phaseolin. These results evidence the promising potential of pinto bean hydrolysates as functional ingredients in the design of healthy foods.
DescripciónTítulo en el postprint: Dual release of peptides and phenolics with antioxidant, ACE-inhibitory and antiinflammatory activities from pinto bean (Phaseolus vulgaris L. var. pinto) proteins by subtilisins
Versión del editorhttp://dx.doi.org/10.1016/j.jff.2015.07.010
URIhttp://hdl.handle.net/10261/124440
DOI10.1016/j.jff.2015.07.010
Identificadoresissn: 1756-4646
Aparece en las colecciones: (ICTAN) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
phaseolus_vulgaris_Garcia.pdf556,29 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.