English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/12319
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Characterization of an inducible transport system for glycerol in Streptomyces clavuligerus. Repression by L-serine

AutorMiñambres Rodríguez, Baltasar ; Reglero, Ángel; Luengo, José M.
Palabras claveEscherichia-coli K-235
Clavulanic acid
Penicillium-Chrysogenum
Coelicolor A3(2)
Wild-type
Biosynthesis
Mutant
Enzyme
Identification
Cultures
Fecha de publicación1992
EditorJapan Antibiotics Research Association
CitaciónThe Journal of Antibiotics 45(2): 269-277 (1992)
ResumenStreptomyces clavuligerus NRRL 3585 grown in a chemically defined medium containing glycerol as the sole carbon source transported this molecule by two different systems. One of these was constitutive with a very low uptake efficiency and insufficient to attend to the metabolic requirements of this bacterium (constitutive glycerol transport system) and the other (glycerol transport system (GTS)) active and specifically induced by D-glycerol which is responsible for the transport of more than 90% of the glycerol taken up the cells. GTS was seen to have an optimal pH and temperature of 7.0 and 30 degrees C, respectively, and its Km was 14 microM. It was repressed by L-serine and addition of this amino acid to the culture broth (10 mM) inhibited the growth of S. clavuligerus but not that of other species of Streptomyces.
Descripción9 pages, 7 figures.-- PMID: 1556020 [PubMed].
URIhttp://hdl.handle.net/10261/12319
ISSN0021-8820
Aparece en las colecciones: (IGM) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
1992_JA_Vol45.pdf7,34 MBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.