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Título

Aromatic metabolism versus carbon availability: the regulatory network that controls catabolism of less-preferred carbon sources in Escherichia coli

AutorPrieto, María Auxiliadora ; Galán, Beatriz ; Torres, Begoña ; Ferrández, Abel; Fernández, Cristina; Miñambres Rodríguez, Baltasar ; García, José Luis ; Díaz, Eduardo
Palabras claveCatabolism
Aromatic compounds
Escherichia coli
Transcriptional regulation
Catabolic pathways
Catabolite repression
CRP
Less-preferred carbon sources
Fecha de publicación2004
EditorFederation of European Microbiological Societies
Elsevier
CitaciónFEMS Microbiology Reviews 28(4): 503-518 (2004)
ResumenThe current knowledge on the genetics and biochemistry of the catabolism of aromatic compounds in Escherichia coli settles the basis to consider these pathways as a model system to study the complex molecular mechanisms that control the expression of the genes involved in the metabolism of less-preferred carbon sources in this paradigmatic organism. Two different levels of regulation are reviewed: (i) the specific regulatory mechanisms that drive the expression of the catabolic genes when the cognate inducer, i.e., the substrate of the pathway or an intermediate metabolite, is available, and (ii) the global or superimposed regulation that adjust the expression of the catabolic clusters to the general physiological status of the cell
Descripción16 pages, 8 figures.-- PMID: 15374664 [PubMed].
Versión del editorhttp://dx.doi.org/10.1016/j.femsre.2004.04.004
URIhttp://hdl.handle.net/10261/12313
DOI10.1016/j.femsre.2004.04.004
ISSN0168-6445
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