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Title: | Inhibitors of sphingolipid metabolism enzymes |
Authors: | Delgado Cirilo, Antonio ![]() ![]() ![]() ![]() ![]() |
Keywords: | Biosynthesis Sphingolipids Metabolism Inhibitor Enzyme |
Issue Date: | 1-Sep-2006 |
Publisher: | Elsevier |
Citation: | Biochimica et Biophysica Acta (BBA)- Biomembranes 1758(12): 1957-1977(2006) |
Abstract: | Sphingolipids are a family of lipids that play essential roles both as structural cell membrane components and in cell signalling. The cellular contents of the various sphingolipid species are controlled by enzymes involved in their metabolic pathways. In this context, the discovery of small chemical entities able to modify these enzyme activities in a potent and selective way should offer new pharmacological tools and therapeutic agents. |
Description: | 21 pages, 31 figures.-- PMID: 17049336 [PubMed].-- Printed version published Dec 2006. |
Publisher version (URL): | http://dx.doi.org/10.1016/j.bbamem.2006.08.017 |
URI: | http://hdl.handle.net/10261/12280 |
DOI: | http://dx.doi.org/10.1016/j.bbamem.2006.08.017 |
ISSN: | 0005-2736 |
Appears in Collections: | (IQAC) Artículos |
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