English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/122794
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

NAPPA as a real new method for protein microarray generation

AuthorsDíez, Paula; González González, María; Lourido, Lucía; Dégano, Rosa M.; Ibarrola, Nieves ; Casado-Vela, Juan; LaBaer, Joshua; Fuentes, Manuel
KeywordsProtein microarray
High-throughput screening
Protein-protein interaction
Microarray generation
Issue Date2015
PublisherMultidisciplinary Digital Publishing Institute
CitationMicroarrays 4(2): 214-227 (2015)
AbstractNucleic Acid Programmable Protein Arrays (NAPPA) have emerged as a powerful and innovative technology for the screening of biomarkers and the study of protein-protein interactions, among others possible applications. The principal advantages are the high specificity and sensitivity that this platform offers. Moreover, compared to conventional protein microarrays, NAPPA technology avoids the necessity of protein purification, which is expensive and time-consuming, by substituting expression in situ with an in vitro transcription/translation kit. In summary, NAPPA arrays have been broadly employed in different studies improving knowledge about diseases and responses to treatments. Here, we review the principal advances and applications performed using this platform during the last years.
DescriptionThis is an open access article distributed under the Creative Commons Attribution License.-- This article belongs to the Special Issue "New and Old Technologies for Generation of Microarrays".
Publisher version (URL)http://dx.doi.org/10.3390/microarrays4020214
Appears in Collections:(IBMCC) Artículos
(CNB) Artículos
Files in This Item:
File Description SizeFormat 
NAPPA as a Real.pdf1,06 MBAdobe PDFThumbnail
Show full item record

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.