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http://hdl.handle.net/10261/122571
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Gomollón-Bel, Fernando | es_ES |
dc.contributor.author | Delso, J. Ignacio | - |
dc.contributor.author | Tejero, Tomás | - |
dc.contributor.author | Merino, Pedro | - |
dc.date.accessioned | 2015-09-24T09:17:38Z | - |
dc.date.available | 2015-09-24T09:17:38Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | Current Chemical Biology 8(1): 10-16 (2014) | - |
dc.identifier.issn | 2212-7968 | - |
dc.identifier.uri | http://hdl.handle.net/10261/122571 | - |
dc.description.abstract | Glycosidase inhibitors are important compounds that can interfere with several biosynthetic processes including N-linked glycosylation and the biosynthesis of several glycoproteins. Understanding the biogenesis of naturally occurring glycosidase inhibitors would be a crucial step towards the chemical synthesis of analogues of choice. This review focuses on the current knowledge regarding the biosynthesis of a series of polyhydroxylated saturated nitrogen heterocycles including nojirimycin and swainsonine among others, with a potent biological activity as inhibitors of glycosidases and transglycosidases. | es_ES |
dc.description.sponsorship | This study was supported by the Ministerio de Ciencia e Innovacion (MICINN) and FEDER Program (Madrid, Spain, project CTQ2010-19606) and the Gobierno de Aragon (Zaragoza, Spain, Bioorganic Chemistry Group. E-10). F.G.- B. thanks CSIC for a JAE predoctoral grant. | - |
dc.language.iso | eng | es_ES |
dc.publisher | Bentham Science Publishers | - |
dc.relation.isversionof | Postprint | es_ES |
dc.rights | openAccess | es_ES |
dc.subject | Biosynthesis | es_ES |
dc.subject | Glycosidase Inhibitors | es_ES |
dc.title | Biosynthetic Pathways to Glycosidase Inhibitors | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.2174/221279680801141112094818 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.2174/221279680801141112094818 | - |
dc.identifier.e-issn | 1872-3136 | - |
dc.contributor.funder | Ministerio de Ciencia e Innovación (España) | es_ES |
dc.contributor.funder | European Commission | - |
dc.contributor.funder | Consejo Superior de Investigaciones Científicas (España) | - |
dc.contributor.funder | Gobierno de Aragón | - |
dc.relation.csic | Sí | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004837 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003339 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100010067 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.languageiso639-1 | en | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.openairetype | artículo | - |
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Fichero | Descripción | Tamaño | Formato | |
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Biosynthetic Pathways.pdf | 596,98 kB | Adobe PDF | Visualizar/Abrir |
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