Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/12231
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dc.contributor.authorLorenzo, Víctor de-
dc.date.accessioned2009-04-13T12:15:18Z-
dc.date.available2009-04-13T12:15:18Z-
dc.date.issued2008-12-
dc.identifier.citationCurrent Opinion in Biotechnology; 19: 6, (2008) 579-589en_US
dc.identifier.issn0958-1669-
dc.identifier.urihttp://hdl.handle.net/10261/12231-
dc.description.abstractBioremediation involves the exposure of a whole mixture of chemical structures to an intricate multispecies metabolic network present in a polluted scenario. The complexity involved in such events is growingly amenable to the conceptual frame and the tools of systems biology. The availability of genes, genomes, and metagenomes of biodegradative micro-organisms make it possible to model and even predict the fate of chemicals through the global metabolic network that results from connecting all known biochemical transactions. Microbial communities thus embody a landscape of pan-enzymes that is shaped by the freely diffusible metabolic pool (epimetabolome). Recent computational resources increasingly help the design of superior biocatalysts for biodegradation and biotransformations of desired chemicals, an objective that capitalizes on the new field of synthetic biology.en_US
dc.description.sponsorshipThe work in Author's Laboratory is funded by contracts of the 6th and 7th Framework Programme of the EU and grants of the Spanish Ministry of Science and Innovation.en_US
dc.format.extent6080 bytes-
dc.format.mimetypeimage/gif-
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsclosedAccessen_US
dc.subjectSystems biologyen_US
dc.subjectBioremediationen_US
dc.titleSystems biology approaches to bioremediationen_US
dc.typeartículoen_US
dc.identifier.doi10.1016/j.copbio.2008.10.004-
dc.description.peerreviewedPeer revieweden_US
dc.relation.publisherversionhttp:dx.doi.org/10.1016/j.copbio.2008.10.004en_US
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.languageiso639-1en-
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