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Título

Bioeutectic® ceramics for biomedical application obtained by laser floating zone method. In vivo evaluation

AutorAza, Piedad N. de; Peña, J. I.; Luklinska, Zofia B.; Meseguer-Olmo, Luis
Palabras claveCalcium phosphate silicate
Implantation
In vivo evaluation
Osseointegration
Fecha de publicación2014
EditorMultidisciplinary Digital Publishing Institute
CitaciónMaterials 7(4): 2395-2410 (2014)
ResumenIn this study, the Bioeutectic® blocks were inserted into the critical size defects of eight rabbits, using both tibiae, and the physical and chemical nature of the remodeled interface between the Bioeutectic® implants and the surrounding bone were performed at four and 15 months. The results showed a new fully mineralized bone growing in direct contact with the implants. The ionic exchange, taking place at the implant interface with the body fluids was essential in the process of the implant integration through a dissolution-precipitation-transformation mechanism. The study found the interface biologically and chemically active over the 15 months implantation period. The osteoblastic cells migrated towards the interface and colonized the surface at the contact areas with the bone. The new developed apatite structure of porous morphology mimics natural bone. © 2014 by the authors.
DescripciónThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.
Versión del editorhttp://dx.doi.org/10.3390/ma7042395
URIhttp://hdl.handle.net/10261/118037
DOI10.3390/ma7042395
Identificadoresdoi: 10.3390/ma7042395
issn: 1996-1944
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