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Title

Effect of bacteriocin-induced cell damage on the branched-chain amino acid transamination by Lactococcus lactis

AuthorsMartínez-Cuesta, M. Carmen ; Requena, Teresa ; Peláez, Carmen
KeywordsLactococcus lactis
Branched-chain amino acid transamination
Bacteriocin-induced cell damage
Issue Date2002
PublisherBlackwell Publishing
CitationFEMS Microbiology Letters 217: 109- 113 (2002)
AbstractThe effect of the bacteriocin lacticin 3147 on the branched-chain amino acid transamination by Lactococcus lactis IFPL359 was investigated. The bacteriocin provokes membrane permeabilisation of the cells, rendering them non-viable but metabolically active. Free diffusion of amino acids into the cell was facilitated. In addition, membrane permeabilisation promotes further cell lysis. Both facts render the enzymes more accessible to their substrates and hence increase branched-chain amino acid transamination. This research broadens the spectrum of technological applications of lacticin 3147 in the development of cheese flavour. © 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
URIhttp://hdl.handle.net/10261/117914
DOI10.1016/S0378-1097(02)01047-9
Identifiersdoi: 10.1016/S0378-1097(02)01047-9
issn: 0378-1097
Appears in Collections:(IF) Artículos
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