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Role of probiotics in obesity management

Other TitlesEl papel de los probióticos en el manejo de la obesidad
AuthorsPrados Bo, Andreu; Gómez Martínez, Sonia CSIC ORCID; Nova, Esther CSIC ORCID ; Marcos, Ascensión CSIC ORCID
Gut microbiota
Issue Date2015
PublisherAula Médica Ediciones
CitationNutricion Hospitalaria 31: 10- 18 (2015)
Abstract© 2015, Grupo Aula Medica S.A. All rights reserved. Obesity is a major public health issue as it is related to several chronic disorders, including type-2 diabetes, high blood pressure, dyslipemia, cardiovascular diseases and cancer, among others. Novel research shows that the gut microbiota is involved in obesity and metabolic disorders, revealing that obese animal and human subjects have alterations in the composition of the gut microbiota compared to their lean counterparts. Moreover, it has been observed in germ-free mice that transplantation of the microbiota of either obese or lean mice influences body weight, suggesting that the gut ecosystem is a relevant target for weight management. Certain strains of probiotics may regulate body weight by influencing the host’s metabolic, neuroendocrine and immune functions. Taken together, our knowledge about the influence of gut microbiota on obesity is progressing. Therefore, modulation of its composition through probiotics may provide new opportunities to manage overweight and obesity.
Identifiersdoi: 10.3305/nh.2015.31.sup1.8702
issn: 1699-5198
Appears in Collections:(ICTAN) Artículos
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