English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/116819
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Stat1 in developing and adult rat brain. Induction after transient focal ischemia

AuthorsPlanas, Anna M. ; Justicia, Carles ; Ferrer, Isidre
Signal transduction
Issue Date1997
PublisherLippincott Williams & Wilkins
CitationNeuroReport 8(6): 1359-1362 (1997)
AbstractSTAT1 has a dual function as signal transducer and activator of transcription, and is activated in response to growth factors and cytokines. We examined Stat1 in the rat brain during development and following transient focal ischemia, using Western immunoblotting. Two bands of 91 and 84 kDa, corresponding to Stat1α and Stat1β forms, were found with an intensity that increased from postnatal day 0 to adulthood in cerebellum and cerebral cortex. Ischemia caused a strong induction of Stat1 in the ipsilateral cortex after 4, 7 and 15 days, but not at 6 or 24 h. These results show that Star1 is normally expressed in the postnatal and adult rat brain and is induced under brain infarction.
Identifiersissn: 0959-4965
Appears in Collections:(IIBB) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
Show full item record
Review this work

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.