English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/115781
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 99 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

The Capsaspora genome reveals a complex unicellular prehistory of animals

AutorSuga, Hiroshi ; Mendoza, Alex de ; Sebé-Pedrós, Arnau ; Sánchez-Pons, Núria ; Torruella, Guifré ; Ruiz-Trillo, Iñaki
Fecha de publicación14-ago-2013
EditorNature Publishing Group
CitaciónNature Communications 4: 2325 (2013)
ResumenTo reconstruct the evolutionary origin of multicellular animals from their unicellular ancestors, the genome sequences of diverse unicellular relatives are essential. However, only the genome of the choanoflagellate Monosiga brevicollis has been reported to date. Here we completely sequence the genome of the filasterean Capsaspora owczarzaki, the closest known unicellular relative of metazoans besides choanoflagellates. Analyses of this genome alter our understanding of the molecular complexity of metazoans' unicellular ancestors showing that they had a richer repertoire of proteins involved in cell adhesion and transcriptional regulation than previously inferred only with the choanoflagellate genome. Some of these proteins were secondarily lost in choanoflagellates. In contrast, most intercellular signalling systems controlling development evolved later concomitant with the emergence of the first metazoans. We propose that the acquisition of these metazoan-specific developmental systems and the co-option of pre-existing genes drove the evolutionary transition from unicellular protists to metazoans. © 2013 Macmillan Publishers Limited. All rights reserved.
DescripciónSuga, Hiroshi et al.-- This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
Versión del editorhttp://dx.doi.org/10.1038/ncomms3325
URIhttp://hdl.handle.net/10261/115781
DOI10.1038/ncomms3325
Identificadoresdoi: 10.1038/ncomms3325
issn: 2041-1723
Aparece en las colecciones: (IBE) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
capsaspora_genome_Suga.pdf909,4 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.