Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/115698
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Fitó, Montserrat | - |
dc.contributor.author | Estruch, Ramón | - |
dc.contributor.author | Salas-Salvadó, Jordi | - |
dc.contributor.author | Martínez-González, Miguel Ángel | - |
dc.contributor.author | Arós, Fernando | - |
dc.contributor.author | Vila, Joan | - |
dc.contributor.author | Corella, Dolores | - |
dc.contributor.author | Díaz, Óscar | - |
dc.contributor.author | Sáez, Guillermo | - |
dc.contributor.author | Torre, Rafael de la | - |
dc.contributor.author | Mitjavila, María Teresa | - |
dc.contributor.author | Muñoz, Miguel Ángel | - |
dc.contributor.author | Lamuela-Raventós, Rosa M. | - |
dc.contributor.author | Ruiz-Gutiérrez, Valentina | - |
dc.contributor.author | Fiol, Miquel | - |
dc.contributor.author | Gómez-Gracia, Enrique | - |
dc.contributor.author | Lapetra, José | - |
dc.contributor.author | Ros, Emilio | - |
dc.contributor.author | Serra-Majem, Lluís | - |
dc.contributor.author | Covas, María Isabel | - |
dc.date.accessioned | 2015-05-25T09:45:57Z | - |
dc.date.available | 2015-05-25T09:45:57Z | - |
dc.date.issued | 2014 | - |
dc.identifier | doi: 10.1002/ejhf.61 | - |
dc.identifier | issn: 1879-0844 | - |
dc.identifier.citation | European Journal of Heart Failure 16: 543- 550 (2014) | - |
dc.identifier.uri | http://hdl.handle.net/10261/115698 | - |
dc.description.abstract | Aims Scarce data are available on the effect of the traditional Mediterranean diet (TMD) on heart failure biomarkers. We assessed the effect of TMD on biomarkers related to heart failure in a high cardiovascular disease risk population. Methods and Results A total of 930 subjects at high cardiovascular risk (420 men and 510 women) were recruited in the framework of a multicentre, randomized, controlled, parallel-group clinical trial directed at testing the efficacy of the TMD on the primary prevention of cardiovascular disease (The PREDIMED Study). Participants were assigned to a low-fat diet (control, n=310) or one of two TMDs [TMD+virgin olive oil (VOO) or TMD+nuts]. Depending on group assignment, participants received free provision of extra-virgin olive oil, mixed nuts, or small non-food gifts. After 1year of intervention, both TMDs decreased plasma N-terminal pro-brain natriuretic peptide, with changes reaching significance vs. control group (P<0.05). Oxidized low-density lipoprotein decreased in both TMD groups (P<0.05), the decrease in TMD+VOO group reaching significance vs. changes in control group (P=0.003). Changes in lipoprotein(a) after TMD+VOO were less than those in the control group (P=0.046) in which an increase (P=0.035) was observed. No changes were observed in urinary albumin or albumin/creatinine ratio. Conclusions Individuals at high risk of cardiovascular disease (CVD) who improved their diet toward a TMD pattern reduced their N-terminal pro-brain natriuretic peptide compared with those assigned to a low-fat diet. The same was found for in vivo oxidized low-density lipoprotein and lipoprotein(a) plasma concentrations after the TMD+VOO diet. From our results TMD could be a useful tool to mitigate against risk factors for heart failure. From our results TMD could modify markers of heart failure towards a more protective mode. © 2014 The Authors. | - |
dc.description.sponsorship | This work has been supported by the Spanish Ministry of Health, Centro Nacional de Investigaciones Cardiovasculares (CNIC) (Project no. 4606005377) | - |
dc.publisher | John Wiley & Sons | - |
dc.rights | closedAccess | - |
dc.subject | Lipoprotein a | - |
dc.subject | Urinary albumin | - |
dc.subject | Albumin/creatinine ratio | - |
dc.subject | Oxidized LDL | - |
dc.subject | Heart failure | - |
dc.subject | N-terminal pro-brain natriuretic peptide | - |
dc.title | Effect of the Mediterranean diet on heart failure biomarkers: A randomized sample from the PREDIMED trial | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1002/ejhf.61 | - |
dc.date.updated | 2015-05-25T09:45:57Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (IG) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
112
checked on 20-abr-2024
WEB OF SCIENCETM
Citations
100
checked on 26-feb-2024
Page view(s)
314
checked on 24-abr-2024
Download(s)
276
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.