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Título

VCF2Networks: Applying genotype networks to single-nucleotide variants data

Autor Dall'Olio, Giovanni Marco; Vahdati, Ali R.; Bertranpetit, Jaume ; Wagner, Andreas; Laayouni, Hafid
Fecha de publicación 2015
EditorOxford University Press
Citación Bioinformatics 31(3): 438-439 (2015)
ResumenA wealth of large-scale genome sequencing projects opens the doors to new approaches to study the relationship between genotype and phenotype. One such opportunity is the possibility to apply genotype networks analysis to population genetics data. Genotype networks are a representation of the set of genotypes associated with a single phenotype, and they allow one to estimate properties such as the robustness of the phenotype to mutations, and the ability of its associated genotypes to evolve new adaptations. So far, though, genotype networks analysis has rarely been applied to population genetics data. To help fill this gap, here we present VCF2Networks, a tool to determine and study genotype network structure from single-nucleotide variant data. © The Author 2014. Published by Oxford University Press. All rights reserved.
Versión del editorhttp://dx.doi.org/10.1093/bioinformatics/btu650
URI http://hdl.handle.net/10261/115690
DOI10.1093/bioinformatics/btu650
Identificadoresdoi: 10.1093/bioinformatics/btu650
e-issn: 1460-2059
issn: 1367-4803
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