English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/115680
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 23 veces en Web of Knowledge®  |  Pub MebCentral Ver citas en PubMed Central  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)
Título

Comparative effect of two Mediterranean diets versus a low-fat diet on glycaemic control in individuals with type 2 diabetes

Autor Lasa, A.; Miranda, J.; Bulló, Mònica; Casas, Rosa; Salas-Salvadó, Jordi; Larretxi, I.; Estruch, Ramón; Ruiz-Gutiérrez, Valentina ; Portillo, María Puy
Palabras clave Low-fat diet
Type 2 diabetes
Glycaemic control
Mediterranean diet
Fecha de publicación 2014
EditorNature Publishing Group
Citación European Journal of Clinical Nutrition 68: 767- 772 (2014)
ResumenBackground/Objectives: Although benefits have been attributed to the Mediterranean diet, its effect on glycaemic control has not been totally elucidated. The aim of this work was to compare the effect of two Mediterranean diets versus a low-fat diet on several parameters and indices related to glycaemic control in type 2 diabetic subjects. Subjects/Methods: A multicentric parallel trial was conducted on 191 participants (77 men and 114 women) of the PREDIMED study in order to compare three dietary interventions: two Mediterranean diets supplemented with virgin olive oil (n=67; body mass index (BMI)=29.4 ± 2.9) or mixed nuts (n = 74; BMI = 30.1 ± 3.1) and a low-fat diet (n = 50; BMI = 29.8 ± 2.8). There were no drop-outs. Changes in body weight and waist circumference were determined. Insulin resistance was measured by HOMA-IR index, adiponectin/leptin and adiponectin/HOMA-R ratios after 1 year of follow-up. Results: Increased values of adiponectin/leptin ratio (P = 0.043, P = 0.001 and P < 0.001 for low-fat, olive oil and nut diets, respectively) and adiponectin/HOMA-IR ratio (P = 0.061, P = 0.027 and P = 0.069 for low-fat, olive oil and nut diets, respectively) and decreased values of waist circumference (P = 0.003, P = 0.001 and P = 0.001 for low-fat, olive oil and nut diets, respectively) were observed in the three groups. In both Mediterranean diet groups, but not in the low-fat diet group, this was associated with a significant reduction in body weight (P = 0.347, P = 0.003 and P = 0.021 for low-fat, olive oil and nut diets, respectively). Conclusions: Mediterranean diets supplemented with virgin olive oil or nuts reduced total body weight and improved glucose metabolism to the same extent as the usually recommended low-fat diet. © 2014 Macmillan Publishers Limited.
URI http://hdl.handle.net/10261/115680
DOI10.1038/ejcn.2014.1
Identificadoresdoi: 10.1038/ejcn.2014.1
issn: 0954-3007
Aparece en las colecciones: (IG) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.