Bimetallic Nanostars (Ag@Au) with High Surface Enhanced Raman Scattering (SERS) Performance: Detection of beta-Amyloid and Its Marker Thioflavin T

Abstract

Developing new synthesis methods to obtain metal nanoparticles (NPs) with three dimensional (3D) surface morphology is very important, due to their physical properties and versatility to diversify their applications[1]. Anisotropic metal NPs with a large variety of sizes and shapes have been recently fabricated displaying good Surface-enhanced Raman Scattering (SERS) properties. In this context, star-shaped NPs or metal nanostars (NS) have shown extraordinary properties in the intensification of the Electro Magnetic field, with promising applications in bioimaging and detection[2]. In this context, core@shell nanoparticles display advantageous properties to be used as SERS substrates. This work was aimed at the fabrication of Ag@Au NS by using AgNS as seeds by simple methods with high effectiveness in SERS and without the use of strong surfactants.