English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/115513
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Population Genomic Analysis of Ancient and Modern Genomes Yields New Insights into the Genetic Ancestry of the Tyrolean Iceman and the Genetic Structure of Europe

AuthorsSikora, Martin; Sánchez-Quinto, Federico ; Bustamante, Carlos D.
Issue Date8-May-2014
PublisherPublic Library of Science
CitationPLoS Genetics 10(5): e1004353 (2014)
AbstractGenome sequencing of the 5,300-year-old mummy of the Tyrolean Iceman, found in 1991 on a glacier near the border of Italy and Austria, has yielded new insights into his origin and relationship to modern European populations. A key finding of that study was an apparent recent common ancestry with individuals from Sardinia, based largely on the Y chromosome haplogroup and common autosomal SNP variation. Here, we compiled and analyzed genomic datasets from both modern and ancient Europeans, including genome sequence data from over 400 Sardinians and two ancient Thracians from Bulgaria, to investigate this result in greater detail and determine its implications for the genetic structure of Neolithic Europe. Using whole-genome sequencing data, we confirm that the Iceman is, indeed, most closely related to Sardinians. Furthermore, we show that this relationship extends to other individuals from cultural contexts associated with the spread of agriculture during the Neolithic transition, in contrast to individuals from a hunter-gatherer context. We hypothesize that this genetic affinity of ancient samples from different parts of Europe with Sardinians represents a common genetic component that was geographically widespread across Europe during the Neolithic, likely related to migrations and population expansions associated with the spread of agriculture. © 2014 Sikora et al.
DescriptionSikora, Martin et al.
Publisher version (URL)http://dx.doi.org/10.1371/journal.pgen.1004353
URIhttp://hdl.handle.net/10261/115513
DOI10.1371/journal.pgen.1004353
ISSN1553-7404
Appears in Collections:(IBE) Artículos
Files in This Item:
File Description SizeFormat 
population_genomic_analysis_Sikora.pdf1,23 MBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.