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Two multidrug-resistant salmonella infantis isolates behave like hypo-invasive strains but have high intracellular proliferation | Dos aislamientos de salmonella infantis multirresistentes se comportan como hipoinvasivos pero con elevada proliferación intracellular

AuthorsConza, José di; Mollerach, Marta; Gutkind, Gabriel; Ayala, Juan Alfonso
Intracelular proliferation
Invasion ability
Issue Date2012
PublisherAsociación Argentina de Microbiología
CitationRevista Argentina de Microbiologia 44: 69-74 (2012)
AbstractIn this work, plasmid-encoded virulence factors in two Salmonella Infantis isolates carrying multiresistance plasmids were investigated. In addition, their invasion and proliferative ability in non-phagocytic cells was studied. None of them showed the typical determinants of virulence plasmids (spv operon). The invasion assays of S. Infantis isolates on eukaryotic cells showed a decreased ability to invade but they remained and proliferated in the cytoplasm regardless of having used a permissive (HeLa) or non-permissive (NRK) cell line. Finally, there was no microscopic evidence suggesting a bactericidal effect of these eukaryotic cell lines on the isolates tested.
Identifiersissn: 0325-7541
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