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Title

Antiproliferative activityon human cancer cellsof phospho- sphingolipids from buttermilk isolated with food grade procedures

AuthorsCastro-Gómez, Pilar ; Monteiro, Karin M.; Rodríguez Alcalá, Luis M. ; Carvalho, João Ernesto de; Fontecha, F. Javier
Issue Date2014
CitationSymposium Sphingolipids in Health and Disease (2014)
AbstractButtermilk (BM), by-product of the elaboration of butter, is a rich source of phospho- and sphingolipids. These compounds have been associated to anticarcinogenic effects or improvement of age-related disease in humans. However, it is unknown if possible effects in buttermilk may be associated to whole lipids, neutral or polar compounds. In a previous study, authors reported that isolation involving chloroform reduced the bioactivity of lipids. The aim of the study was to evaluate the antiproliferative effect on 9 human cancer cell (glioma, breast, ovary, kidney, lung, colon, leukemia and keratinocytes) of powder buttermilk (PBM), total fat and neutral and polar lipids fractions isolated with food grade methods.
DescriptionTrabajo presentado al Symposium Sphingolipids in Health and Disease celebrado en el Instituto de Biología Molecular y Celular de Oporto (Portugal) el 18 de septiembre de 2014.
Publisher version (URL)http://www.ibmc.up.pt/sphingosymp/index.html
URIhttp://hdl.handle.net/10261/115090
Appears in Collections:(CIAL) Comunicaciones congresos
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