English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/114046
COMPARTIR / IMPACTO:
Estadísticas
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
Título

Intestinal preconditioning is mediated by a transient increase in nitric oxide

AutorHotter, Georgina ; Closa, Daniel ; Prados, M.C.; Fernández-Cruz, Laureano; Prats, Neus; Gelpí, Emili ; Roselló-Catafau, Joan
Fecha de publicación1-may-1996
EditorAcademic Press
CitaciónBiochemical and Biophysical Research Communications 222(1): 27-32 (1996)
ResumenThe effect of ischemic preconditioning on the intestine, as well the implication of nitric oxide and prostacyclin in this process has been evaluated. Thus, intestinal ischemia-reperfusion was induced in rats, and the protection conferred by previous preconditioning was evaluated. In addition, the effect of nitric oxide inhibition and the administration of nitric oxide were determined. Results show that the increases observed in LDH release after ischemia-reperfusion were prevented after preconditioning. Inhibition of nitric oxide synthesis abolished the protective effect of preconditioning, and nitric oxide administration replicated this effect. Also, an increased synthesis of nitric oxide has been detected after preconditioning. Increases in 6 keto PGF(1α) were independent of nitric oxide. Altogether indicates that preconditioning is triggered by an initial increase in nitric oxide synthesis.
Versión del editorhttp://dx.doi.org/10.1006/bbrc.1996.0692
URIhttp://hdl.handle.net/10261/114046
DOI10.1006/bbrc.1996.0692
Identificadoresdoi: 10.1006/bbrc.1996.0692
issn: 0006-291X
Aparece en las colecciones: (IIBB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 

Artículos relacionados:


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.