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dc.contributor.authorMané-Padrós, Daniel-
dc.contributor.authorCruz, Josefa-
dc.contributor.authorBellés, Xavier-
dc.contributor.authorMartín Casacuberta, David A.-
dc.identifier.citation18th International Ecdysone Workshop (2010)-
dc.descriptionTrabajo presentado en el 18th International Ecdysone Workshop, celebrado del 19 al 23 de julio en Ceske Budejovice (República Checa).-
dc.description.abstractIn hemimetabolan insects, post-embryonic development presents remarkably differences with respect to holometabolan species, in that growth and maturation occur simultaneously throughout successive nymphal stages until the imaginal molt. This type of development, relatively similar to that of vertebrates, contrasts with that presented by holometabolan insects in which an intermediate pupal stage occurs between the larval and adult stages. In holometabolan insects, growth is restricted to larval development whereas maturation occurs during metamorphosis in the pupal stage. A common feature in both types of development, however, is that the ecdysteroid hormone 20-hydroxyecdysone (20E) controls all developmental transitions. Periodic pulses of 20E trigger juvenile molts and, in holometabolan insects, a pulse of 20E at the end of the last larval instar signals the onset of pupariation where it controls the destruction of larval tissues and the formation of the adult structures during metamorphosis. Although there is a detailed understanding of the molecular mechanisms by which 20E regulates the unique metamorphic process in holometabolan insects, little is known about how this hormone operates during the development of hemimetabolan insects. If we aim to understand the molecular basis of the evolution towards complete metamorphosis in insects, then functional characterization of the 20E-induced genetic hierarchy in hemimetabolan species becomes of paramount importance. In this context, we have isolated the majority of the components of this hierarchy in the cockroach Blattella germanica. By using a RNAi in vivo strategy, here we show that a complex cross-regulatory interplay between different 20E-dependent nuclear receptors, namely BgEcR, BgRXR, BgE75, BgHR3, BgHR4 and BgFTZ-F1 tightly controls most of the biological responses to 20E during nymphal and adult development in B. germanica.-
dc.titleMetamorphosis in hemimetabolous insects. Characterization of the ecdysone regulatory cascade in the cockroach Blattella germanica-
dc.typecomunicación de congreso-
dc.description.versionPeer Reviewed-
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