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Título

Changes in the immune system are conditioned by nutrition

AutorMarcos, Ascensión ; Nova, Esther ; Montero, A.
Palabras claveImmunity
Eating disorders
Physiological situations
Malnutrition
Fecha de publicación2003
EditorNature Publishing Group
CitaciónEuropean Journal of Clinical Nutrition 57: S66- S69 (2003)
ResumenUndernutrition due to insufficient intake of energy and macronutrients and/or due to deficiencies in specific micronutrients impairs the immune system, suppressing immune functions that are fundamental to host protection. The most consistent abnormalities are seen in cell-mediated immunity, complement system, phagocyte function, cytokine production, mucosal secretory antibody response, and antibody affinity. There is a number of physiological situations such as ageing and performance of intense physical exercise associated with an impairment of some immune parameters' response. Nutrition can influence the extent of immune alteration in both of them. There are also numerous pathological situations in which nutrition plays a role as a primary or secondary determinant of some underlying immunological impairments. This includes obesity, eating disorders (anorexia nervosa and bulimia nervosa), food hypersensitivity and gastrointestinal disorders as some examples. The implications of nutrition on immune function in these disorders are briefly reviewed.
URIhttp://hdl.handle.net/10261/113981
DOI10.1038/sj.ejcn.1601819
Identificadoresdoi: 10.1038/sj.ejcn.1601819
issn: 0954-3007
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