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http://hdl.handle.net/10261/113632
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dc.contributor.author | Arques, María del Carmen | - |
dc.contributor.author | Marín-Manzano, M. Carmen | - |
dc.contributor.author | Brito da Rocha, L. Clarissa | - |
dc.contributor.author | Hernández-Ledesma, Blanca | - |
dc.contributor.author | Recio, Isidra | - |
dc.contributor.author | Clemente, Alfonso | - |
dc.date.accessioned | 2015-04-14T09:30:09Z | - |
dc.date.available | 2015-04-14T09:30:09Z | - |
dc.date.issued | 2014 | - |
dc.identifier | doi: 10.1016/j.foodchem.2014.01.024 | - |
dc.identifier | issn: 0308-8146 | - |
dc.identifier.citation | Food Chemistry 155: 24-30 (2014) | - |
dc.identifier.uri | http://hdl.handle.net/10261/113632 | - |
dc.description.abstract | Naturally-occurring serine protease inhibitors of the Bowman-Birk family exert their potential chemopreventive and/or therapeutic properties via protease inhibition. In this study, we have quantified the amounts of active BBI isoinhibitors, IBB1 and IBBD2, in six commercial soymilks. By using cation exchange chromatography, the BBI isoinhibitors were isolated and their specific trypsin inhibitory activity was used to estimate their amounts in soymilk samples. IBB1 and IBBD2 concentrations ranged from 0.44 to 5.20 and 0.27 to 4.60 mg/100 ml of soymilk, respectively; total BBI, considered as the sum of both isoinhibitors, ranged from 0.60 to 9.07 mg/100 ml of soymilk. These data show that physiologically relevant amounts of active BBI are present in commercial soymilk and may exert potential health-promoting effects. | - |
dc.description.sponsorship | A.C. acknowledges support by ERDF-co-financed Grant from the Spanish CICYT (AGL2011-26353). A.C. is involved in COST Action FA1005 INFOGEST on Food Digestion. L.C.B.R. acknowledges support from CAPES (Programa Institucional de Doutorado Sanduíche no Exterior–PDSE process number 9004-11-4), Brazil. We are grateful to the proteomics Facility of University of Cordoba (Spain) for carrying out peptide mass fingerprinting. B.H.-L. thanks Ministry of Economy and Competitiveness for her “Ramón y Cajal” contract. | - |
dc.publisher | Elsevier | - |
dc.relation.isversionof | Postprint | - |
dc.rights | openAccess | - |
dc.subject | Kunitz | - |
dc.subject | Chemoprevention | - |
dc.subject | Protease inhibitors | - |
dc.subject | Serine proteases | - |
dc.subject | Soymilk | - |
dc.subject | Bowman-Birk inhibitors | - |
dc.title | Quantitative determination of active Bowman-Birk isoinhibitors, IBB1 and IBBD2, in commercial soymilks | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1016/j.foodchem.2014.01.024 | - |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.foodchem.2014.01.024 | - |
dc.embargo.terms | 2015-07-15 | - |
dc.date.updated | 2015-04-14T09:30:09Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.contributor.funder | Comisión Interministerial de Ciencia y Tecnología, CICYT (España) | - |
dc.contributor.funder | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil) | - |
dc.contributor.funder | Universidad de Córdoba (España) | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100007273 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100002322 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
Aparece en las colecciones: | (EEZ) Artículos (CIAL) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
revised manuscript soymilk BBI .pdf | 289,05 kB | Adobe PDF | Visualizar/Abrir | |
Figure 1mod.pdf | 116,8 kB | Adobe PDF | Visualizar/Abrir |
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