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dc.contributor.authorMontero, Ana-
dc.contributor.authorMann, Enrique-
dc.contributor.authorHerradón García, Bernardo-
dc.date.accessioned2009-03-06T13:24:13Z-
dc.date.available2009-03-06T13:24:13Z-
dc.date.issued2005-02-17-
dc.identifier.citationTetrahedron Letters 46(3): 401-405 (2005)en_US
dc.identifier.issn0040-4039-
dc.identifier.urihttp://hdl.handle.net/10261/11334-
dc.description5 pages, 1 figure, 2 schemes.-- Available online Dec 8, 2004.-- Taken in part from the Ph.D. thesis of AM.en_US
dc.description.abstractA stereocontrolled synthesis of an unsaturated sugar bearing two amino groups (one of them masked as an azide), using an Overman rearrangement as key step, is described. This scaffold is used to prepare two peptides having aromatic fragments, which have shown activity as calpain inhibitors.en_US
dc.description.sponsorshipFinancial support from Janssen-Cilag and Spanish Ministry of Science and Technology (project # BQU2001-2270) is gratefully acknowledged. A.M. thanks CSIC for an EPO-fellowship.en_US
dc.format.extent918459 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.rightsclosedAccessen_US
dc.subjectAmino sugaren_US
dc.subjectCalpain inhibitoren_US
dc.subjectEnkephalinen_US
dc.subjectOverman rearrangementen_US
dc.subjectPeptidomimeticen_US
dc.titleThe Overman rearrangement in carbohydrate chemistry: stereoselective synthesis of functionalized 3-amino-3,6-dihydro-2H-pyrans and incorporation in peptide derivativesen_US
dc.typeartículoen_US
dc.identifier.doi10.1016/j.tetlet.2004.11.109-
dc.description.peerreviewedPeer revieweden_US
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.tetlet.2004.11.109en_US
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.languageiso639-1en-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairetypeartículo-
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