English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/113044
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:

Title

Novel synthesis, molecular structure, and theoretical studies of dispiro compounds via pseudo-eight-component reaction

AuthorsHazeri, Nourallah; Lashkari, Mojtaba; García-Granda, Santiago CSIC ORCID; Torre-Fernández, Laura
Issue Date2014
PublisherCSIRO Publishing
CitationAustralian Journal of Chemistry 67(11): 1656-1665 (2014)
AbstractWe have developed a diastereoselective synthesis of dispiro compounds through a one-pot domino pseudo-eight-component reaction of amines, aldehydes, and Meldrum's acid. This method resulted in the generation of complex products with four stereocentres and involves formation of 10 new bonds. Quantum mechanical calculations were undertaken in order to determine the stability of the eight diastereomer structures of compound 4a. The crystal structure of 4k was determined by X-ray crystallography. Reaction mechanism can proceed through Knoevenagel, Aldol condensations, Diels-Alder cycloaddition, and Michael addition.
URIhttp://hdl.handle.net/10261/113044
DOIhttp://dx.doi.org/10.1071/CH13713
Identifiersdoi: 10.1071/CH13713
issn: 0004-9425
e-issn: 1445-0038
Appears in Collections:(CINN) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.