English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/112684
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Citado 89 veces en Web of Knowledge®  |  Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar otros formatos: Exportar EndNote (RIS)Exportar EndNote (RIS)Exportar EndNote (RIS)
Título

Localization of 5-HT4 receptor mRNA in rat brain by in situ hybridization histochemistry

Autor Vilaró, Maria Teresa ; Cortés, Roser ; Gerald, Christoph; Branchek, Theresa A.; Palacios, José M.; Mengod Los Arcos, Guadalupe
Palabras clave 5-HT4 receptor
Splice variant
Basal ganglia
Pre-synaptic receptor
[125I]SB 207710
Fecha de publicación 31-dic-1996
EditorElsevier
Citación Molecular Brain Research 43(1-2): 356-360 (1996)
ResumenOligonucleotide probes that recognize two cloned splice variants (5-HT(4S) and 5-HT(4L)) of 5-HT4 receptors were used to study by in situ hybridization the localization in rat brain of mRNA encoding these receptors. A probe common to both variants reveals high levels of transcripts in olfactory tubercle, some components of the basal ganglia (caudate putamen, ventral striatum), medial habenula and hippocampal formation. Similar patterns of distribution are obtained with probes that recognize each splice variant individually, suggesting that no dramatic differences exist in their respective regional distribution. Comparison of mRNA distribution with receptor distribution as visualized with [125I]SB 207710 indicates that 5-HT4 receptors are localized both somatodendritically in e.g. caudate putamen and on axon terminals in e.g. substantia nigra and globus pallidus.
Versión del editorhttp://dx.doi.org/10.1016/S0169-328X(96)00248-3
URI http://hdl.handle.net/10261/112684
DOI10.1016/S0169-328X(96)00248-3
Identificadoresdoi: 10.1016/S0169-328X(96)00248-3
issn: 0169-328X
Aparece en las colecciones: (IIBB) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
accesoRestringido.pdf15,38 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 



NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.