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Title

A new approach for the synthesis of bisindoles through AgOTf as catalyst

AuthorsBeltrá, Jorge; Gimeno, M. Concepción ; Herrera, Raquel P.
Issue Date2014
PublisherBeilstein-Institut zur Förderung der Chemischen Wissenschaften
CitationBeilstein Journal of Organic Chemistry 10: 2206-2214 (2014)
AbstractA novel approach for the catalyzed formation of bisindolylmethane derivatives (BIMs) is described. This methodology is the unique example where AgOTf has been successfully used for the activation of aldehydes, giving easy access to a broad range of bisindolyl derivatives with excellent results. Moreover, the simplicity and easy operational methodology using a small amount of commercially available AgOTf (1-3 mol %), one of the lowest catalytic charge used in this process to date, makes this procedure an alternative approach for this interesting and appealing reaction.
DescriptionThis is an Open Access article under the terms of the Creative Commons Attribution License.
Publisher version (URL)http://dx.doi.org/10.3762%2Fbjoc.10.228
URIhttp://hdl.handle.net/10261/111879
DOI10.3762%2Fbjoc.10.228
Identifiersdoi: 10.3762/bjoc.10.228
issn: 1860-5397
Appears in Collections:(ISQCH) Artículos
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