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Título:	Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation
Autor:	Jorcano, José L.; Larcher, Fernando; Acedo, Pablo
Fecha de publicación:	2014
Editor:	Optical Society of America
Citación:	Biomedical Optics Express 5(9): 3231-3237 (2014)
Resumen:	In this study the first results on evaluation and assessment of grafted bioengineered skin substitutes using an optical Diffuse Reflectance Spectroscopy (DRS) system with a remote optical probe are shown. The proposed system is able to detect early vascularization of skin substitutes expressing the Vascular Endothelial Growth Factor (VEGF) protein compared to normal grafts, even though devitalized skin is used to protect the grafts. Given the particularities of the biological problem, data analysis is performed using two Blind Signal Separation (BSS) methods: Principal Component Analysis (PCA) and Independent Component Analysis (ICA). These preliminary results are the first step towards point-of-care diagnostics for skin implants early assessment.
Descripción:	et al.
Versión del editor:	http://dx.doi.org/10.1364/BOE.5.003231
URI:	http://hdl.handle.net/10261/111636
DOI:	10.1364/BOE.5.003231
ISSN:	2156-7085
Aparece en las colecciones:	(IIBM) Artículos

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Remote diffuse reflectance spectroscopy sensor for tissue engineering monitoring based on blind signal separation