Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/111509
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | García-Moreno, Elena | - |
dc.contributor.author | Cerrada, Elena | - |
dc.contributor.author | Bolsa, M. José | - |
dc.contributor.author | Luquin, Asunción | - |
dc.contributor.author | Laguna, Mariano | - |
dc.date.accessioned | 2015-02-27T12:07:53Z | - |
dc.date.available | 2015-02-27T12:07:53Z | - |
dc.date.issued | 2013 | - |
dc.identifier | doi: 10.1002/ejic.201201411 | - |
dc.identifier | issn: 1434-1948 | - |
dc.identifier.citation | European Journal of Inorganic Chemistry 12: 2020-2030 (2013) | - |
dc.identifier.uri | http://hdl.handle.net/10261/111509 | - |
dc.description.abstract | New water-soluble phosphanes derived from 1,3,5-triaza-7-phosphaadamantane, namely, [PTA-R]Br (R = -CH2C≡CH, -CH2CONH 2, -CH2COOH), are described. Coordination of these phosphanes and their previously reported counterparts (R = -CH2CN, -CH2Ph and -CH2COOMe) to gold(I) salts gives water-soluble derivatives with chlorido, bromido or pentafluorophenyl coligands. The luminescence properties of all new compounds have been studied in the solid state and compared with the respective free PTA ligands. [PTA-CH 2Ph]Br, [PTA-CH2COOMe]Br and [AuBr(PTA-CH 2Ph)]Br have also been characterised by X-ray diffraction analysis. Some of the new gold(I) compounds exhibit strong antiproliferative effects in the human ovarian carcinoma cell line A2780 and its cisplatin-resistant variant (A2780cisR). A balanced relationship between lipophilicity and hydrophilicity is found in these derivatives, with distribution coefficients (log D 7.4) that range from 0.14 to -0.40. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | - |
dc.description.sponsorship | We thank the Ministerio de Ciencia e Innovación (MICINN) (grant number CTQ2008-06716-CO3-01) for financial support and Torrecid SA for a generous donation of H[AuCl4] | - |
dc.publisher | Wiley-VCH | - |
dc.rights | closedAccess | - |
dc.title | Water-soluble phosphanes derived from 1,3,5-triaza-7-phosphaadamantane and their reactivity towards gold(I) complexes | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1002/ejic.201201411 | - |
dc.date.updated | 2015-02-27T12:07:53Z | - |
dc.description.version | Peer Reviewed | - |
dc.language.rfc3066 | eng | - |
dc.contributor.funder | Ministerio de Ciencia e Innovación (España) | - |
dc.contributor.funder | Torrecid Group | - |
dc.relation.csic | Sí | - |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004837 | es_ES |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
Aparece en las colecciones: | (ISQCH) Artículos |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
accesoRestringido.pdf | 15,38 kB | Adobe PDF | Visualizar/Abrir |
CORE Recommender
SCOPUSTM
Citations
27
checked on 20-abr-2024
WEB OF SCIENCETM
Citations
27
checked on 29-feb-2024
Page view(s)
200
checked on 22-abr-2024
Download(s)
106
checked on 22-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.