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Title

In utero and post-natal accumulation of organochlorine compounds in children under different environmental conditions

AuthorsCarrizo, Daniel; Grimalt, Joan O. ; Ribas-Fitó, Núria; Torrent, Maties; Sunyer, Jordi
KeywordsOrganochlorine compounds
Accumulation
In utero
Post-natal
Contamination
Issue Date14-May-2007
PublisherRoyal Society of Chemistry (UK)
CitationJournal of Environmental Monitoring 9(6): 523-529 (2007)
AbstractA study of intake of organochlorine compounds (OCs) in children both in utero and at the age of four years has been performed in two cohorts. One encompasses children born in Menorca Island between 1997 and 1998, and the other those born between 1997–1999 in Ribera d’Ebre, an in-land industrial–agricultural area of Catalonia. Comparison of the OC concentrations in serum samples from both populations, including those obtained from cord blood and blood collected at four years, provides information on the influence of local pollution sources in the accumulation of these compounds. Statistically significant differences (p < 0.01) have been found for hexachlorobenzene, indicating that chronic airborne contamination to this compound in Ribera d’Ebre involved higher in utero exposure, which increased in the first four years of growth. Similarly, in the cohort of Menorca, higher in utero exposure to PCBs was observed and this increased subsequently in the first four years of growth. Other compounds encompassing temporal contamination episodes such as g-HCH involved higher in utero exposure but strongly diminished in the first four years of growth. Overall, it can be concluded that local chronic pollution by OCs has a direct effect in children living in the surrounding areas. This influence is reflected in higher exposure, both in utero and in the first years of growth, that significantly stands out over the background contamination due to the ubiquity of these compounds.
Description7 pages, 3 figures, 3 pages.-- PMID: 17554423 [PubMed].
Publisher version (URL)http://dx.doi.org/10.1039/b700247e
URIhttp://hdl.handle.net/10261/11126
DOI10.1039/b700247e
ISSN1464-0325
E-ISSN1464-0333
Appears in Collections:(IDAEA) Artículos
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