English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/111097
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Diversity of structures and properties among catalases

AuthorsChelikani, Prashen; Fita, Ignacio ; Loewen, Peter C.
KeywordsCrystal structure
Dimanganese
Heme
Peroxidase
Catalase
Issue DateJan-2004
PublisherBirkhäuser Verlag
CitationCellular and Molecular Life Sciences 61(2): 192-208 (2004)
AbstractMore than 300 catalase sequences are now available, divided among monofunctional catalases (> 225), bifunctional catalase-peroxidases (> 50) and manganese-containing catalases (> 25). When combined with the recent appearance of crystal structures from at least two representatives from each of these groups (nine from the monofunctional catalases), valuable insights into the catalatic reaction mechanism in its various forms and into catalase evolution have been gained. The structures have revealed an unusually large number of modifications unique to catalases, a result of interacting with reactive oxygen species. Biochemical and physiological characterization of catalases from many different organisms has revealed a surprisingly wide range of catalatic efficiencies, despite similar sequences. Catalase gene expression in micro-organisms generally is controlled either by sensors of reactive oxygen species or by growth phase regulons, although the detailed mechanisms vary considerably.
Publisher version (URL)http://dx.doi.org/10.1007/s00018-003-3206-5
URIhttp://hdl.handle.net/10261/111097
DOI10.1007/s00018-003-3206-5
Identifiersdoi: 10.1007/s00018-003-3206-5
issn: 1420-682X
Appears in Collections:(IBMB) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.