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Design and Validation of a Neuroprosthesis for the Treatment of Upper Limb Tremor

AuthorsGallego, Juan Álvaro CSIC ORCID CVN; Rocón, Eduardo CSIC ORCID; Belda-Lois, Juan Manuel; Koutsou, Aikaterini CSIC ORCID CVN; Mena, Silvia; Castillo, Ascensión; Pons Rovira, José Luis CSIC ORCID
Issue Date2013
CitationEngineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE
AbstractPathological tremor is the most prevalent movement disorder. In spite of the existence of various treatments for it, tremor poses a functional problem to a large proportion of patients. This paper presents the design and implementation of a novel neuroprosthesis for tremor management. The paper starts by reviewing a series of design criteria that were established after analyzing users needs and the expected functionality of the system. Then, it summarizes the design of the neuroprosthesis, which was built to meet the criteria defined previously. Experimental results with a representative group of 12 patients show that the neuroprosthesis provided significant (p < 0.001) and systematic tremor attenuation (in average 52.33 ± 25.48 %), and encourage its functional evaluation as a potential new treatment for tremor in a large cohort of patients.
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