English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/10917
Compartir / Impacto:
Estadísticas
Add this article to your Mendeley library MendeleyBASE
Ver citas en Google académico
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Título

Tick-bite-induced anaphylaxis in Spain

AutorFernández Soto, Pedro; Dávila, I.; Laffond, E.; Lorente, F.; Encinas Grandes, Antonio; Pérez Sánchez, Ricardo
Fecha de publicaciónene-2001
EditorRoutledge
CitaciónAnnals of Tropical Medicine and Parasitology 95(1): 97-103 (2001)
ResumenAlthough there are very few reports of human anaphylaxis induced by tick bites, two such cases have recently been seen in Salamanca, Spain. To identify the tick species responsible, salivary-gland extracts from six species of hard tick and two of soft tick were prepared and used as allergens/antigens in skin-prick tests and serological analyses. For each case, the results of the skin tests were positive for several species of hard tick but negative for the soft ticks. ELISA and western blots revealed high titres of IgG against hard ticks (but not soft ticks) in the sera from both cases. However, serum from only one of the cases was found to be ELISA- and western-blot-positive for tick-specific IgE. Accordingly, the anaphylaxis seen in one case was IgE-mediated whereas that in the other case appeared to be IgE-independent. In both cases, most of the tick-specific antibodies only recognized carbohydrate epitopes. High levels of cross-reactivity between the salivary-gland extracts from several species of hard tick made it impossible to identify which species was responsible for each anaphylactic reaction, although the immunolgical results seem to point to Ixodes ricinus.
Descripción7 pages, 2 figures.-- PMID: 11235559 [PubMed].
Versión del editorhttp://www.ingentaconnect.com/content/routledg/catm/2001/00000095/00000001/art00011?token=004810966720297d76253e7b3a4a45242442422c496d3f6a4b6e4e395e4e6b63314fe220
URIhttp://hdl.handle.net/10261/10917
ISSN0003-4983
Aparece en las colecciones: (IRNASA) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
Tick-bite-induced.pdf58,96 kBAdobe PDFVista previa
Visualizar/Abrir
Mostrar el registro completo
 


NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.