English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/10518
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Exportar a otros formatos:

Title

LC-MS for identifying photodegradation products of pharmaceuticals in the environment

AuthorsPetrovic, Mira ; Barceló, Damià
KeywordsLiquid chromatography
Mass spectrometry
Pharmaceuticals
Photodegradation
Transformation product
Issue Date24-Feb-2007
PublisherElsevier
CitationTrAC-Trends in Analytical Chemistry 26(6): 486-493 (2007)
AbstractAbiotic processes, such as direct and indirect photolysis, are of great importance in determining the aquatic fate of pharmaceutical compounds. Photolytic reactions are often complex, involving various competing or parallel pathways and leading to multiple reaction products. The identification of transformation products and the elucidation of photolysis-reaction pathways are of crucial importance in understanding their fate in the aquatic environment, but are complicated and cumbersome.
This article focuses on advanced liquid chromatography-mass spectrometry (LC-MS) methods for identifying transformation products of abiotic processes that lead to the transformation of pharmaceutical compounds in environmental systems (direct and indirect photolysis) and photocatalytic transformations in water- and wastewater-treatment systems, using titanium dioxide or the photo-Fenton process.
We discuss the capabilities and the limitations of single-MS, tandem-MS and hybrid-MS techniques, and present practical examples (triple-quadrupole-MS analysis of phototransformation products of fluoxetine, ion-trap-MS analysis of photoproducts of carbamazepine, and time-of-flight-MS elucidation of the reaction pathways of photolytic and photocatalytic degradation of diclofenac).
Description8 pages, 4 figures, 1 table.-- Printed version published Jun 2007.-- Issue title: Pharmaceutical-residue analysis.
Publisher version (URL)http://dx.doi.org/10.1016/j.trac.2007.02.010
URIhttp://hdl.handle.net/10261/10518
DOIhttp://dx.doi.org/10.1016/j.trac.2007.02.010
ISSN0167-2940
Appears in Collections:(IDAEA) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.