English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/10518
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

LC-MS for identifying photodegradation products of pharmaceuticals in the environment

AutorPetrovic, Mira; Barceló, Damià
Palabras claveLiquid chromatography
Mass spectrometry
Transformation product
Fecha de publicación24-feb-2007
CitaciónTrAC-Trends in Analytical Chemistry 26(6): 486-493 (2007)
ResumenAbiotic processes, such as direct and indirect photolysis, are of great importance in determining the aquatic fate of pharmaceutical compounds. Photolytic reactions are often complex, involving various competing or parallel pathways and leading to multiple reaction products. The identification of transformation products and the elucidation of photolysis-reaction pathways are of crucial importance in understanding their fate in the aquatic environment, but are complicated and cumbersome.
This article focuses on advanced liquid chromatography-mass spectrometry (LC-MS) methods for identifying transformation products of abiotic processes that lead to the transformation of pharmaceutical compounds in environmental systems (direct and indirect photolysis) and photocatalytic transformations in water- and wastewater-treatment systems, using titanium dioxide or the photo-Fenton process.
We discuss the capabilities and the limitations of single-MS, tandem-MS and hybrid-MS techniques, and present practical examples (triple-quadrupole-MS analysis of phototransformation products of fluoxetine, ion-trap-MS analysis of photoproducts of carbamazepine, and time-of-flight-MS elucidation of the reaction pathways of photolytic and photocatalytic degradation of diclofenac).
Descripción8 pages, 4 figures, 1 table.-- Printed version published Jun 2007.-- Issue title: Pharmaceutical-residue analysis.
Versión del editorhttp://dx.doi.org/10.1016/j.trac.2007.02.010
Aparece en las colecciones: (IDAEA) Artículos
Ficheros en este ítem:
No hay ficheros asociados a este ítem.
Mostrar el registro completo

Artículos relacionados:

NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.