English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/102114
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Endowing single-chain polymer nanoparticles with enzyme-mimetic activity

AuthorsPérez-Baena, Irma ; Barroso-Bujans, Fabienne ; Gasser, Urs; Arbe, Arantxa ; Moreno Segurado, Ángel J. ; Colmenero de León, Juan ; Pomposo, José A.
Issue Date2013
PublisherAmerican Chemical Society
CitationACS Macro Letters 2(9): 775-779 (2013)
AbstractThe development of simple, efficient, and robust strategies affording the facile construction of biomimetic organocatalytic nano-objects is currently a subject of great interest. Herein, a new pathway to artificial organocatalysts based on partially collapsed individual soft nano-objects displaying useful and diverse biomimetic catalytic functions is reported. Single-chain polymer nanoparticles endowed with enzyme-mimetic activity synthesized following this new route display (i) a relatively extended morphology under good solvent conditions, as revealed by small angle neutron scattering and coarse-grained molecular dynamics simulation results, (ii) multiple, compartmentalized, and accessible catalytic sites in which borane catalytic units are retained via B···O interactions, and (iii) unprecedented reductase and polymerase enzyme-mimetic properties. © 2013 American Chemical Society.
Publisher version (URL)http://dx.doi.org/10.1021/mz4003744
Identifiersdoi: 10.1021/mz4003744
e-issn: 2161-1653
Appears in Collections:(CFM) Artículos
Files in This Item:
File Description SizeFormat 
Endowing single-chain.pdf761,21 kBAdobe PDFThumbnail
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.