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Título: | Solvent-free synthesis of α-amino nitrile-derived ureas |
Autor: | Ventosa-Andrés, Pilar CSIC; González-Vera, Juan A. CSIC ORCID; García-López, M. Teresa CSIC ; Herranz, Rosario CSIC ORCID | Fecha de publicación: | 2013 | Editor: | American Chemical Society | Citación: | Organic Letters 15: 632- 635 (2013) | Resumen: | An efficient and environmentally friendly methodology for the solvent-free synthesis of α-amino nitrile derived ureas from α-amino acid based amino nitriles has been developed. At room temperature no epimerization was observed in the resulting ureas, but under microwave heating, epimerization occurred at the chiral center bearing the cyano group. | URI: | http://hdl.handle.net/10261/101666 | DOI: | 10.1021/ol303452r | Identificadores: | doi: 10.1021/ol303452r issn: 1523-7060 e-issn: 1523-7052 |
Aparece en las colecciones: | (IQM) Artículos |
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Org Lett-2013.pdf | 511,78 kB | Adobe PDF | Visualizar/Abrir |
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