English   español  
Por favor, use este identificador para citar o enlazar a este item: http://hdl.handle.net/10261/101457
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Quantum dots and superparamagnetic nanoparticles interaction with pathogenic fungi: internalization and toxicity profile

AutorRispail, Nicolas ; Matteis, Laura de; Custardoy, Laura; Testillano, P.S. ; Risueño, María Carmen ; Pérez de Luque, Alejandro ; Fernández-Pacheco, Rodrigo; Ibarra, M. Ricardo; Fuente, Jesús M. de la; Marquina, Clara; Rubiales, Diego ; Prats, Elena
Palabras claveSuperparamagnetic nanoparticles
Quatum dots
Fusarium oxysporum
Disease control
Plant pathogens
Fecha de publicación22-may-2014
EditorAmerican Chemical Society
CitaciónACS Applied Materials and Interfaces 6(12): 9100–9110 (2014)
ResumenFor several years now, nanoscaled materials are being implemented in biotechnological applications related to animal (in particular human) cells and related pathologies. However, the use of nanomaterials in plant biology is far less widespread, although their application in this field could lead to the future development of plant biotechnology applications. For any practical use, it is crucial to elucidate the relationship between the nanomaterials and the target cells. In this work we have evaluated the behaviour of two types of nanomaterials, quantum dots and superparamagnetic nanoparticles, on Fusarium oxysporum, a fungal species that infects an enormous range of crops causing important economic losses and is also an opportunistic human pathogen. Our results indicated that both nanomaterials rapidly interacted with the fungal hypha labeling the presence of the pathogenic fungus, although they showed differential behaviour with respect to internalization. Thus, whereas magnetic nanoparticles appeared to be on the cell surface, quantum dots were significantly taken up by the fungal hyphae showing their potential for the development of novel control approaches for F. oxysporum and related pathogenic fungi following appropriate functionalization. In addition, the fungal germination and growth, accumulation of ROS, indicative of cell stress, and fungal viability have been evaluated at different nanomaterial concentrations showing the low toxicity of both types of nanomaterials to the fungus. This work represents the first study on the behavior of quantum dots and superparamagnetic particles on fungal cells, and constitutes the first and essential step to address the feasibility of new nanotechnology-based systems for early detection and eventual control of pathogenic fungi.
DescripciónRispail, Nicolas et.al.
Versión del editorhttp://dx.doi.org/10.1021/am501029g
Aparece en las colecciones: (CIB) Artículos
(ICMA) Artículos
(IAS) Artículos
Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
submitted_version.pdf1,18 MBAdobe PDFVista previa
Mostrar el registro completo

Artículos relacionados:

NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.