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AccR is a master regulator involved in carbon catabolite repression of the anaerobic catabolism of aromatic compounds in azoarcus sp. CIB

AuthorsValderrama, J. Andrés ; Shingler, Victoria; Carmona, Manuel ; Díaz, Eduardo
KeywordsAnaerobic degradation
Response regulator
Transcriptional regulation
Carbon catabolite repression
Issue Date3-Dec-2013
PublisherAmerican Society for Biochemistry and Molecular Biology
CitationJournal of Biological Chemistry 289 (4) 1892- 1904 (2014)
AbstractBackground: Mechanisms underlying carbon catabolite repression (CCR) control of the anaerobic degradation of aromatic compounds have previously remained elusive. Results: Phosphorylated AccR was identified as a transcriptional repressor of aromatic degradation operons expressed under anaerobic conditions. Conclusion: The response regulator AccR controls the succinate-dependent CCR in Azoarcus sp. CIB. Significance: AccR is a master regulator that controls anaerobic CCR in bacteria. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.
Description14 p.-9 fig.-2 tab.
Publisher version (URL)http://dx.doi.org/10.1074/jbc.M113.517714
Appears in Collections:(CIB) Artículos
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