English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/100157
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Maedi-Visna: the meningoencephalitis in naturally occurring cases

AuthorsBenavides, Julio ; García Pariente, C.; Fuertes, M. ; Ferreras, Mª del Carmen ; García Marín, Juan Francisco ; Juste, R. A.; Pérez Pérez, Valentín
KeywordsMeningoencephalitis
Sheep
Viral infection
Maedi-visna
Demyelination
Lentivirus
Issue Date2009
PublisherElsevier
CitationJournal of Comparative Pathology 140: 1- 12 (2009)
AbstractLesions were examined at different levels of the central nervous system (CNS) in 64 sheep with natural maedi-visna (MV) meningoencephalitis. All animals showed lesions in more than one of the CNS locations examined; the lesions in the cranial regions were periventricular, while those in the spinal cord affected the white matter funicles. Lesions were found particularly in the cerebellar peduncles (non-suppurative meningoencephalitis), followed by the corpus callosum, hippocampus and thoracic spinal cord. Vascular, infiltrative and malacic histopathological patterns were recognized. One pattern predominated in each section examined, although mixed forms occurred. Vascular lesions occurred with similar frequency at all CNS levels, but infiltrative and malacic lesions predominated at rostral and caudal levels, respectively. Cells consistent with macrophages and shown immunohistochemically to be associated with MV virus were seen in malacic and infiltrative lesions, at the periphery of damaged areas.
Description12 páginas, 5 figuras, 2 tablas.
Publisher version (URL)http://dx.doi.org/10.1016/j.jcpa.2008.07.010
URIhttp://hdl.handle.net/10261/100157
DOI10.1016/j.jcpa.2008.07.010
ISSN1532-3129
Appears in Collections:(IGM) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdf15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.