2024-03-28T19:16:40Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/70632021-07-28T12:07:10Zcom_10261_125com_10261_2col_10261_378
Competitive exclusion of enteropathogens from human intestinal mucus by Bifidobacterium strains with acquired resistance to bile : A preliminary study
Gueimonde Fernández, Miguel
Margolles Barros, Abelardo
González de los Reyes-Gavilán, Clara
Salminen, Seppo
Academy of Finland
European Commission
Comisión Interministerial de Ciencia y Tecnología, CICYT (España)
Bifidobacterias
Enteropatógenos
Probióticos
The ability to inhibit the adhesion and to displace selected pathogens from human intestinal mucus of two Bifidobacterium strains with acquired resistance to bile, were assessed and compared with those of their bile sensitive original strains. A preliminary characterization of the macromolecules involved in the adhesion was also carried out. The inhibition of adhesion and the displacement of enteropathogens previously adhered were found to be specific, depending on the strains used. The cholate-resistant strain Bifidobacterium bifidum M6dCo, that adhered more to mucus than its original, was able to inhibit the adhesion and to displace pathogens from mucus significantly more than its original cholate-sensitive strain B. bifidum M6. Contrary to this, two strains showing similar adhesion levels, B. bifidum Al and its bile resistant derivative B. bifidum AldOx, did not display any differences. Different molecules appear to be involved in the adhesion of the strains B. bifidum M6 and B. bifidum M6dCo. These differences in the cellular surface may explain the differences in competitive exclusion observed between both strains.
2008-09-02T11:25:03Z
2008-09-02T11:25:03Z
2007
artículo
International Journal of Food Microbiology 113: 228–232 (2007)
0168-1605
http://hdl.handle.net/10261/7063
10.1016/j.ijfoodmicro.2006.05.017
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100007273
http://dx.doi.org/10.13039/501100002341
eng
closedAccess
Elsevier