2024-03-28T19:33:54Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/50972021-12-27T16:55:45Zcom_10261_44com_10261_4com_10261_25com_10261_1col_10261_297col_10261_278
SOS-Independent Induction of dinB Transcription by β-Lactam-Mediated Inhibition of Cell Wall Synthesis in Escherichia coli
Pérez-Capilla, Tatiana
Baquero, María del Rosario
Gómez-Gómez, José María
Ionel, Alina
Martín, Soledad
Blázquez, Jesús
Transcription of the dinB gene, encoding DNA polymerase IV, is induced by the inhibition of cell wall synthesis at different levels. Using the β-lactam antibiotic ceftazidime, a PBP3 inhibitor, as a model, we have shown that this induction is independent of the LexA/RecA regulatory system. Induction of dinB transcription mediated by ceftazidime produces an increase in the reversion of a +1 Lac frameshift mutation.
2008-06-13T12:26:47Z
2008-06-13T12:26:47Z
2005-02
artículo
Journal of Bacteriology 187(4): 1515–1518 (2005)
1098-5530
http://hdl.handle.net/10261/5097
10.1128/JB.187.4.1515-1518.2005
15687217
eng
http://dx.doi.org/10.1128/JB.187.4.1515-1518.2005
closedAccess
American Society for Microbiology