2024-03-28T16:59:32Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/2374382021-04-10T02:31:16Zcom_10261_11773com_10261_1col_10261_11774
Influence of Three Dental Implant Surfaces on Cell Viability and Bone Behavior. An In Vitro and a Histometric Study in a Rabbit Model
Rizo-Gorrita, María
Fernandez-Asian, Ignacio
García de Frenza, Andreina
Vázquez-Pachón, Celia
Serrera-Figallo, María-Ángeles
Torres-Lagares, Daniel
Gutiérrez-Pérez, José-Luis
Ziacom Medical
Dental implant surfaces
Surface roughness
Titanium
Osseointegration
Bone–implant interface
© 2020 by the authors.
The chemical composition and the surface characteristics of dental implants are factors that have a decisive effect on the osseointegration process. The surface characterization at the compositional and topographic level of three dental implants available in the market was performed with different surface treatments: (1) sandblasted and acid etched surface (SLA), (2) hydroxyapatite (HA) and tricalcium phosphate (TCP) blasted surface (HA/TCP), and (3) HA-blasted and non-etching acid washed surface (HA + AW). In addition, an in vitro viability study of MG-63 osteoblast cells was performed with a JC-1 test. To complete the study, an in vivo study was conducted in New Zealand rabbits. The study analyzed the histometric characteristics of the bone formed around the implants at the level of area, volume, bone density, accumulated bone density, and bone–implant contact (BIC). The rabbits were sacrificed at 6 weeks after implants were placed in the tibial metaphysis. No statistically significant differences were observed at the level of cell viability or histometric parameters between the different study groups (p > 0.05). SLA and HA/TCP surfaces were the ones that obtained a higher BIC value. Taking into account the limitations of this study, it can be concluded that the different implant surfaces analyzed favor a good bone response.
2021-04-09T09:40:04Z
2021-04-09T09:40:04Z
2020
2021-04-09T09:40:04Z
artículo
Applied Sciences 10(14): 4790(2020)
http://hdl.handle.net/10261/237438
10.3390/app10144790
2076-3417
Publisher's version
http://dx.doi.org/10.3390/app10144790
Sí
http://creativecommons.org/licenses/by/4.0/
openAccess