2024-03-19T03:26:44Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1625232020-12-10T16:52:12Zcom_10261_56com_10261_3col_10261_309
Contribution of bioactive hyaluronic acid and gelatin to regenerative medicine. Methodologies of gels preparation and advanced applications
Mora-Boza, Ana
Puertas-Bartolomé, María
Vázquez-Lasa, Blanca
San Román, Julio
Pérez-Caballer, Antonio
Olmeda-Lozano, Marta
Ministerio de Economía, Industria y Competitividad (España)
An overview of the most relevant crosslinking processes and agents that are being developed for regenerative medicine, including different hydrogel modifications as well as several interesting and advanced applications. The functionality and reactivity of polysaccharides and in particular hyaluronic acid in combination with proteins like gelatin, collagen and many others offer very interesting opportunities for the new trends in regenerative medicine. The biomimetic approaches for the application in regenerative processes and tissue engineering have enormous possibilities because of the excellent response of these biomimetic materials and their bioactive and biodegradable character in the human body. These characteristics together with the possibility of application by minimally invasive surgery offer very interesting applications in regeneration of tissues and organs, as well as in targeting and releasing of bioactive compounds applications as drug delivery systems. In addition, the growing of clinical applications of these macromolecular components as assemblies opens new and advanced opportunities in regenerative medicine and drug delivery fields.
2018-03-20T09:07:26Z
2018-03-20T09:07:26Z
2017
2018-03-20T09:07:27Z
artículo
European Polymer Journal 95: 11-26 (2017)
http://hdl.handle.net/10261/162523
10.1016/j.eurpolymj.2017.07.039
http://dx.doi.org/10.13039/501100010198
eng
http://dx.doi.org/10.1016/j.eurpolymj.2017.07.039
Sí
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2014-51918-C2-1-R
closedAccess
Elsevier