2024-03-29T05:48:11Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/152752020-07-03T12:48:40Zcom_10261_5062com_10261_5com_10261_41com_10261_1col_10261_5064col_10261_294
Distribution of endocrine disruptors in the Llobregat River basin (Catalonia, NE Spain)
Céspedes, Raquel
Lacorte Bruguera, Silvia
Raldúa, Demetrio
Ginebreda Martí, Antoni
Barceló, Damià
Piña, Benjamín
Endocrine disrupting compounds
Estrogenicity
Liquid chromatography–mass spectrometry
Recombinant yeast assay
10 pages, 3 figures.-- PMID: 15893793 [PubMed].-- Printed version published Dec 2005.
The Llobregat basin is a Mediterranean fluvial system with major agricultural, urban and industrial impacts. We combined chemical quantification by liquid chromatography–mass spectrometry with electrospray interface (LC-ESI-MS) and the recombinant yeast assay (RYA) assays to estimate the loads of endocrine disrupting compounds (EDCs) along the basin. Chemical analysis revealed maximum concentrations (at μg l−1 level) of alkylphenols at the lower course of the Llobregat River, which correlated with high levels of estrogenic activity detected by RYA. Analysis by RYA and LC-ESI-MS of influent and effluent waters from four sewage treatment plants (STP) discharging into the basin showed the removal of 80–95% of EDCs by STP treatment. Chemical analysis data and RYA data showed a quasi-linear correlation, demonstrating the complementariness of both methods. Our data suggest that the concentrations of the analysed compounds were enough to explain the total estrogenicity of water and STP samples from the Llobregat basin.
2009-07-24T07:43:04Z
2009-07-24T07:43:04Z
2005-05-12
artículo
Chemosphere 61(11): 1710-1719 (2005)
0045-6535
http://hdl.handle.net/10261/15275
10.1016/j.chemosphere.2005.03.082
1879-1298
eng
http://dx.doi.org/10.1016/j.chemosphere.2005.03.082
closedAccess
Elsevier