2024-03-28T08:18:26Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/14512023-01-05T09:03:56Zcom_10261_131com_10261_2col_10261_384
Zera®, a novel technology for stable accumulation and easy recovery of recombinant proteins in eukaryotic protein-production hosts
Llop, I.
Torrent, Maties
Marzabal, P.
Bastida, M.
Llompart, Blanca
Ludevid, M. Dolors
First paragraph (this article has no abstract) Subcellular targeting of proteins in host cells is one of the most important issues in protein production. Stability, folding, and post-translational modifications depend on where proteins are sorted. Besides secretion, ER appears as an efficient compartment to accumulate proteins, as demonstrated by the frequent use of K/HDEL fused to the C-terminus of a protein to retain and accumulate recombinant proteins in the endoplasmic reticulum (ER) of the cell hosts.
2007-05-08T16:42:59Z
2007-05-08T16:42:59Z
2006-10-10
artículo
Microbial Cell Factories 2006, 5(Suppl 1):S42
1475-2859
http://hdl.handle.net/10261/1451
10.1186/1475-2859-5-S1-S42
eng
Publisher’s version
openAccess
BioMed Central