2024-03-29T11:45:22Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1441162022-11-23T11:36:07Zcom_10261_108com_10261_8col_10261_361
Characterization of Anaplasma phagocytophilum and A. ovis infection in a naturally infected sheep flock with poor health condition
Torina, Alessandra
Galindo, Ruth C.
Vicente, Joaquín
Di Marco, Vincenzo
Alongi, Angelina
Caracappa, Santo
Kocan, Katherine M.
Gortázar, Christian
Fuente, José de la
Ministerio de Ciencia e Innovación (España)
Ministerio de Educación y Ciencia (España)
Ministero della Salute
European Commission
msp4
Epidemiology
Sheep
Genetics
Anaplasma
Tick
Anaplasma species are transmitted by ticks and cause diseases in humans and animals. These pathogens infect sheep, an economically important domestic animal worldwide. The current study was designed to characterize in 200 animals the infection with Anaplasma phagocytophilum and Anaplasma ovis and the genetic diversity of A. ovis strains collected from a naturally infected sheep flock with poor health condition. Sheep had 98% seroprevalence to Anaplasma spp. antibodies. PCR results confirmed the presence of A. phagocytophilum and A. ovis DNA in 11.5% and 37% of the sheep, respectively. Concurrent infections were detected in 6.5% of the sheep. Seventy-one adult ticks were collected from 45 sheep with infestations ranging from one to 15 ticks per animal. The analysis of A. ovis msp4 sequences demonstrated a previously unreported polymorphism for this pathogen with 17 different haplotypes in infected sheep. These results demonstrated that, although A. ovis msp4 haplotypes may be less variable when compared with Anaplasma marginale and A. phagocytophilum strains on a global scale, genetic polymorphisms occur in this locus in strains obtained from an infected sheep flock with poor health condition.
2017-02-16T13:43:17Z
2017-02-16T13:43:17Z
2010
2017-02-16T13:43:18Z
artículo
Tropical Animal Health and Production 42(7): 1327-1331 (2010)
http://hdl.handle.net/10261/144116
10.1007/s11250-010-9580-8
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/501100003196
eng
Sí
closedAccess
Springer