2024-03-29T12:05:33Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/536152021-09-06T10:48:35Zcom_10261_68com_10261_2col_10261_321
Low-fat dairy products and blood pressure: Follow-up of 2290 older persons at high cardiovascular risk participating in the PREDIMED study
Toledo, Estefanía
Delgado-Rodríguez, Miguel
Estruch, Ramón
Salas-Salvadó, Jordi
Corella, Dolores
Gómez-Gracia, Enrique
Fiol, Miquel
Lamuela-Raventós, Rosa M.
Schröder, Helmut
Arós, Fernando
Ros, Emilio
Ruiz-Gutiérrez, Valentina
Lapetra, José
Conde-Herrera, Manuel
Sáez, Guillermo
Vinyoles, Ernest
Martínez-González, Miguel Ángel
Low-fat dairy products
Blood pressure
Dietary pattern
Cardiovascular risks
PREDIMED study
High blood pressure (BP) has been ranked as the most important risk factor worldwide regarding attributable deaths. Dietary habits are major determinants of BP. Among them, frequent intake of low-fat dairy products may protect against hypertension. Our aim was to assess the relationship between low-fat dairy product intake and BP levels and their changes after 12-month follow-up in a cohort of asymptomatic older persons at high cardiovascular risk recruited into a large-scale trial assessing the effects of Mediterranean diets on cardiovascular outcomes. Data from 2290 participants, including 1845 with hypertension, were available for analyses. Dairy products were not a specific part of the intervention; thus, data were analysed as an observational cohort. Dietary information was collected with validated semi-quantitative FFQ and trained personnel measured BP. To assess BP changes, we undertook cross-sectional analyses at baseline and at the end of follow-up and longitudinal analyses. A statistically significant inverse association between low-fat dairy product intake and systolic BP was observed for the 12-month longitudinal analysis. In the longitudinal analysis, the adjusted systolic and diastolic BP were significantly lower in the highest quintile of low-fat dairy product intake (-4.2 (95% CI -6.9, -1.4) and -1.8 (95% CI -3.2, -0.4) mmHg respectively), whereas the point estimates for the difference in diastolic BP indicated a modest non-significant inverse association. Intake of low-fat dairy products was inversely associated with BP in an older population at high cardiovascular risk, suggesting a possible protective effect against hypertension. © The Author 2008.
The PREDIMED study is funded by public resources from the Spanish Ministry of Health (Fondo de Investigación Sanitaria PI04233, PI051839, PI070240, PI052368, PI052584, PI051458, PI042234, RTIC G03/140, RD06/0045/0000 and CIBER CB06/03 Fisiopatología de la Obesidad y Nutrición) and from the Generalitat Valenciana (GRUPOS2004-43 and ACOMP06109).
Peer Reviewed
2012-07-20T08:03:26Z
2012-07-20T08:03:26Z
2009-01
2012-07-20T08:03:26Z
artículo
http://purl.org/coar/resource_type/c_6501
doi: 10.1017/S0007114508981496
issn: 0007-1145
e-issn: 1475-2662
British Journal of Nutrition 101(1): 59-67 (2009)
PMID: 18492300
http://hdl.handle.net/10261/53615
10.1017/S0007114508981496
es
open
Cambridge University Press