2024-03-28T20:54:19Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/375642021-12-28T16:44:24Zcom_10261_75com_10261_6col_10261_328
Linkage map construction involving a reciprocal translocation
Farré, A.
Lacasa-Benito, I.
Cistué Sola, Luis
de Jong, J. H.
Romagosa, Ignacio
Jansen, J.
33 Pag., 5 Fig. The definitive version is available at: http://www.springerlink.com/content/0040-5752/
This paper is concerned with a novel statistical–genetic approach for the construction of linkage maps in populations obtained from reciprocal translocation heterozygotes of barley (Hordeum vulgare L.). Using standard linkage analysis, translocations usually lead to ‘pseudo-linkage’: the mixing up of markers from the chromosomes involved in the translocation into a single linkage group. Close to the translocation breakpoints recombination is severely suppressed and, as a consequence, ordering markers in those regions is not feasible. The novel strategy presented in this paper is based on (1) disentangling the “pseudo-linkage” using principal coordinate analysis, (2) separating individuals into translocated types and normal types and (3) separating markers into those close to and those more distant from the translocation breakpoints. The methods make use of a consensus map of the species involved. The final product consists of integrated linkage maps of the distal parts of the chromosomes involved in the translocation.
This study has been supported by the Spanish Ministry of Science and Innovation (Project AGL2008-05541-C02 and the Agrogenomics CONSOLIDER).
Peer reviewed
2011-07-07T11:38:18Z
2011-07-07T11:38:18Z
2011-03
artículo
http://purl.org/coar/resource_type/c_6501
Farré A, Lacasa I, Cistué L, de Jong JH, Romagosa I, Jansen J. Linkage map construction involving a reciprocal translocation. Theoretical and applied genetics 122 (5): 1029-1037 (2011)
0040-5752
http://hdl.handle.net/10261/37564
10.1007/s00122-010-1507-2
1432-2242
21153624
en
http://dx.doi.org/10.1007/s00122-010-1507-2
open
Springer