2024-03-29T00:34:29Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/2105362020-10-26T18:39:52Zcom_10261_86com_10261_1col_10261_339
Developmental expression of H3.3A variant histone mRNA in mouse
López-Fernández, Luis A.
López-Alañón, Dulce M.
Castañeda, Vianney
Krimer, Dora B.
Del Mazo, Jesús
Dirección General de Investigación Científica y Técnica, DGICT (España)
European Commission
Instituto de Salud Carlos III
Comunidad de Madrid
Krimer, Dora B. [0000-0001-9972-3994]
Del Mazo, Jesús [0000-0003-3269-3895]
H3.3A-cap
Variant histone
Gene expression
5 p.-8 fig.
Cloning and characterization of H3.3A variant histone expression has recently been reported to be associated with meiotic development in mouse testis and ovary. Using Northern analysis and in situ hybridization, the pattern of H3.3A expression was studied during the development of different tissues. In addition to the differential expression detected in male and female meiosis, H3.3A was found to be highly expressed in preantral follicles of adult ovaries and in the basal regions of seminiferous epithelium corresponding to spermatogonia. Different patterns of expression were observed in somatic tissues, which also differed with respect to the developmental stage of the tissue. The lowest expression was detected in adult skeletal muscle. High expressions were found in foetal liver and spinal cord. These different expressions might reflect a possible function of H3.3A in cell differentiation as detected in MEL cells.
This work was supported by grants from the DGICYT (PB92-0063,PB9S-0119) and The European Commission PL 960183 to JM. and from the FIS (93/0161) and CAM (AE 001 18/94) to DK.
Peer reviewed
2020-05-06T08:36:18Z
2020-05-06T08:36:18Z
1997-10
artículo
http://purl.org/coar/resource_type/c_6501
Int J Dev Biol 41(5) 699-703 (1997)
0214-6282
http://hdl.handle.net/10261/210536
1696-3547
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/100012818
http://dx.doi.org/10.13039/501100008737
http://dx.doi.org/10.13039/501100004587
en
Publisher's version
http://www.ijdb.ehu.es/web/paper.php?doi=9415489
Sí
open
Universidad del País Vasco